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Vitamin C alleviates aging defects in a stem cell model for Werner syndrome

Werner syndrome (WS) is a premature aging disorder that mainly affects tissues derived from mesoderm. We have recently developed a novel human WS model using WRN-deficient human mesenchymal stem cells (MSCs). This model recapitulates many phenotypic features of WS. Based on a screen of a number of c...

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Detalles Bibliográficos
Autores principales: Li, Ying, Zhang, Weizhou, Chang, Liang, Han, Yan, Sun, Liang, Gong, Xiaojun, Tang, Hong, Liu, Zunpeng, Deng, Huichao, Ye, Yanxia, Wang, Yu, Li, Jian, Qiao, Jie, Qu, Jing, Zhang, Weiqi, Liu, Guang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930768/
https://www.ncbi.nlm.nih.gov/pubmed/27271327
http://dx.doi.org/10.1007/s13238-016-0278-1