Prospective study of the UGT1A1*27 gene polymorphism during irinotecan therapy in patients with lung cancer: Results of Lung Oncology Group in Kyusyu (LOGIK1004B)

BACKGROUND: Uridine 5′‐diphospho‐glucuronosyltransferase 1A1 (UGT1A1*27) is known to impair the effect of UGT in basic research; however, little clinical investigation has been conducted. To evaluate the effect of the UGT1A1*27 polymorphism in irinotecan therapy, we conducted a prospective study. ME...

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Detalles Bibliográficos
Autores principales: Fukuda, Minoru, Suetsugu, Takayuki, Shimada, Midori, Kitazaki, Takeshi, Hashiguchi, Kohji, Kishimoto, Junji, Harada, Taishi, Seto, Takashi, Ebi, Noriyuki, Takayama, Koichi, Sugio, Kenji, Semba, Hiroshi, Nakanishi, Yoichi, Ichinose, Yukito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930967/
https://www.ncbi.nlm.nih.gov/pubmed/27385990
http://dx.doi.org/10.1111/1759-7714.12360

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