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Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Endothelial to mesenchymal transition (EndMT) plays a major role during development, and also contributes to several adult cardiovascular diseases. Importantly, mesenchymal cells including fibroblasts are prominent in atherosclerosis, with key functions including regulation of: inflammation, matrix...
Autores principales: | Evrard, Solene M., Lecce, Laura, Michelis, Katherine C., Nomura-Kitabayashi, Aya, Pandey, Gaurav, Purushothaman, K-Raman, d'Escamard, Valentina, Li, Jennifer R., Hadri, Lahouaria, Fujitani, Kenji, Moreno, Pedro R., Benard, Ludovic, Rimmele, Pauline, Cohain, Ariella, Mecham, Brigham, Randolph, Gwendalyn J., Nabel, Elizabeth G., Hajjar, Roger, Fuster, Valentin, Boehm, Manfred, Kovacic, Jason C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931033/ https://www.ncbi.nlm.nih.gov/pubmed/27340017 http://dx.doi.org/10.1038/ncomms11853 |
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