Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2

Most human genes generate multiple protein isoforms through alternative pre-mRNA splicing, but the mechanisms controlling alternative splicing choices by RNA binding proteins are not well understood. These proteins can have multiple paralogs expressed in different cell types and exhibiting different...

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Detalles Bibliográficos
Autores principales: Keppetipola, Niroshika M., Yeom, Kyu-Hyeon, Hernandez, Adrian L., Bui, Tessa, Sharma, Shalini, Black, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931110/
https://www.ncbi.nlm.nih.gov/pubmed/27288314
http://dx.doi.org/10.1261/rna.057505.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931110/
https://www.ncbi.nlm.nih.gov/pubmed/27288314
http://dx.doi.org/10.1261/rna.057505.116

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