The essential function of the Trypanosoma brucei Trl1 homolog in procyclic cells is maturation of the intron-containing tRNA(Tyr)

Trypanosoma brucei, the etiologic agent of sleeping sickness, encodes a single intron-containing tRNA, tRNA(Tyr), and splicing is essential for its viability. In Archaea and Eukarya, tRNA splicing requires a series of enzymatic steps that begin with intron cleavage by a tRNA-splicing endonuclease an...

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Detalles Bibliográficos
Autores principales: Lopes, Raphael R.S., Silveira, Gilbert de O., Eitler, Roberta, Vidal, Raphael S., Kessler, Alan, Hinger, Scott, Paris, Zdeněk, Alfonzo, Juan D., Polycarpo, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931112/
https://www.ncbi.nlm.nih.gov/pubmed/27284166
http://dx.doi.org/10.1261/rna.056242.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931112/
https://www.ncbi.nlm.nih.gov/pubmed/27284166
http://dx.doi.org/10.1261/rna.056242.116

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