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G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme

Lysine-specific histone demethylase 1 (LSD1) is an essential epigenetic regulator in metazoans and requires the co-repressor element-1 silencing transcription factor (CoREST) to efficiently catalyze the removal of mono- and dimethyl functional groups from histone 3 at lysine positions 4 and 9 (H3K4/...

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Detalles Bibliográficos
Autores principales: Hirschi, Alexander, Martin, William J., Luka, Zigmund, Loukachevitch, Lioudmila V., Reiter, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931117/
https://www.ncbi.nlm.nih.gov/pubmed/27277658
http://dx.doi.org/10.1261/rna.057265.116