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G-quadruplex RNA binding and recognition by the lysine-specific histone demethylase-1 enzyme
Lysine-specific histone demethylase 1 (LSD1) is an essential epigenetic regulator in metazoans and requires the co-repressor element-1 silencing transcription factor (CoREST) to efficiently catalyze the removal of mono- and dimethyl functional groups from histone 3 at lysine positions 4 and 9 (H3K4/...
Autores principales: | Hirschi, Alexander, Martin, William J., Luka, Zigmund, Loukachevitch, Lioudmila V., Reiter, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931117/ https://www.ncbi.nlm.nih.gov/pubmed/27277658 http://dx.doi.org/10.1261/rna.057265.116 |
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