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Memory of cell shape biases stochastic fate decision-making despite mitotic rounding

Cell shape influences function, and the current model suggests that such shape effect is transient. However, cells dynamically change their shapes, thus, the critical question is whether shape information remains influential on future cell function even after the original shape is lost. We address t...

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Detalles Bibliográficos
Autores principales: Akanuma, Takashi, Chen, Cong, Sato, Tetsuo, Merks, Roeland M. H., Sato, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931277/
https://www.ncbi.nlm.nih.gov/pubmed/27349214
http://dx.doi.org/10.1038/ncomms11963