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Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis

Clusterin (CLU) is a stress‐activated molecular chaperone that confers treatment resistance to taxanes when highly expressed. While CLU inhibition potentiates activity of taxanes and other anti‐cancer therapies in preclinical models, progression to treatment‐resistant disease still occurs implicatin...

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Detalles Bibliográficos
Autores principales: Al Nakouzi, Nader, Wang, Chris Kedong, Beraldi, Eliana, Jager, Wolfgang, Ettinger, Susan, Fazli, Ladan, Nappi, Lucia, Bishop, Jennifer, Zhang, Fan, Chauchereau, Anne, Loriot, Yohann, Gleave, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931290/
https://www.ncbi.nlm.nih.gov/pubmed/27198502
http://dx.doi.org/10.15252/emmm.201506059

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