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Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development

Single-cell RNA-sequencing offers unprecedented resolution of the continuum of state transition during cell differentiation and development. However, tools for constructing multi-branching cell lineages from single-cell data are limited. Here we present Mpath, an algorithm that derives multi-branchi...

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Detalles Bibliográficos
Autores principales: Chen, Jinmiao, Schlitzer, Andreas, Chakarov, Svetoslav, Ginhoux, Florent, Poidinger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931327/
https://www.ncbi.nlm.nih.gov/pubmed/27356503
http://dx.doi.org/10.1038/ncomms11988