MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy

MLP (muscle LIM protein)-deficient mice count among the first mouse models for dilated cardiomyopathy (DCM), yet the exact role of MLP in cardiac signalling processes is still enigmatic. Elevated PKCα signalling activity is known to be an important contributor to heart failure. Here we show that MLP...

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Detalles Bibliográficos
Autores principales: Lange, Stephan, Gehmlich, Katja, Lun, Alexander S., Blondelle, Jordan, Hooper, Charlotte, Dalton, Nancy D., Alvarez, Erika A., Zhang, Xiaoyu, Bang, Marie-Louise, Abassi, Yama A., dos Remedios, Cristobal G., Peterson, Kirk L., Chen, Ju, Ehler, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931343/
https://www.ncbi.nlm.nih.gov/pubmed/27353086
http://dx.doi.org/10.1038/ncomms12120

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