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In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study

Light chain (AL) amyloidosis, caused by deposition of amyloidogenic immunoglobulin light chains (LCs), is the most common systemic form in industrialized countries. Still open questions, and premises for developing targeted therapies, concern the mechanisms of amyloid formation in vivo and the bases...

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Detalles Bibliográficos
Autores principales: Ami, Diletta, Lavatelli, Francesca, Rognoni, Paola, Palladini, Giovanni, Raimondi, Sara, Giorgetti, Sofia, Monti, Luca, Doglia, Silvia Maria, Natalello, Antonino, Merlini, Giampaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931462/
https://www.ncbi.nlm.nih.gov/pubmed/27373200
http://dx.doi.org/10.1038/srep29096