ATRA modulates mechanical activation of TGF-β by pancreatic stellate cells

The hallmark of pancreatic ductal adenocarcinoma (PDAC) is abundant desmoplasia, which is orchestrated by pancreatic stellate cells (PSCs) and accounts for the majority of the stroma surrounding the tumour. Healthy PSCs are quiescent, but upon activation during disease progression, they adopt a myof...

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Detalles Bibliográficos
Autores principales: Sarper, Muge, Cortes, Ernesto, Lieberthal, Tyler J., del Río Hernández, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931506/
https://www.ncbi.nlm.nih.gov/pubmed/27375161
http://dx.doi.org/10.1038/srep27639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931506/
https://www.ncbi.nlm.nih.gov/pubmed/27375161
http://dx.doi.org/10.1038/srep27639

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