A systematic High-Content Screening microscopy approach reveals key roles for Rab33b, OATL1 and Myo6 in nanoparticle trafficking in HeLa cells

Synthetic nanoparticles are promising tools for imaging and drug delivery; however the molecular details of cellular internalization and trafficking await full characterization. Current knowledge suggests that following endocytosis most nanoparticles pass from endosomes to lysosomes. In order to des...

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Detalles Bibliográficos
Autores principales: Panarella, Angela, Bexiga, Mariana G., Galea, George, O’ Neill, Elaine D., Salvati, Anna, Dawson, Kenneth A., Simpson, Jeremy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931513/
https://www.ncbi.nlm.nih.gov/pubmed/27374232
http://dx.doi.org/10.1038/srep28865

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