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Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment

To investigate whether overexpression of Bmi1 in lymphocytes can stimulate skeletogenesis by improving the osteogenic microenvironment, we examined the skeletal phenotype of EμBmi1 transgenic mice with overexpression of Bmi1 in lymphocytes. The size of the skeleton, trabecular bone volume and osteob...

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Detalles Bibliográficos
Autores principales: Zhou, Xichao, Dai, Xiuliang, Wu, Xuan, Ji, Ji, Karaplis, Andrew, Goltzman, David, Yang, Xiangjiao, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931581/
https://www.ncbi.nlm.nih.gov/pubmed/27373231
http://dx.doi.org/10.1038/srep29171

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