Topical and Targeted Delivery of siRNAs to Melanoma Cells Using a Fusion Peptide Carrier

Topical application of siRNAs through the skin is a potentially effective strategy for the treatment of melanoma tumors. In this study, we designed a new and safe fusion peptide carrier SPACE-EGF to improve the skin and cell penetration function of the siRNAs and their targeting ability to B16 cells...

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Detalles Bibliográficos
Autores principales: Ruan, Renquan, Chen, Ming, Sun, Sijie, Wei, Pengfei, Zou, Lili, Liu, Jing, Gao, Dayong, Wen, Longping, Ding, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931591/
https://www.ncbi.nlm.nih.gov/pubmed/27374619
http://dx.doi.org/10.1038/srep29159

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