Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci

OBJECTIVES: Genome-wide association studies (GWAS) have identified loci reproducibly associated with inflammatory bowel disease (IBD) and other immune-mediated diseases; however, the molecular mechanisms underlying most of genetic susceptibility remain undefined. Expressional quantitative trait loci...

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Detalles Bibliográficos
Autores principales: Di Narzo, Antonio F, Peters, Lauren A, Argmann, Carmen, Stojmirovic, Aleksandar, Perrigoue, Jacqueline, Li, Katherine, Telesco, Shannon, Kidd, Brian, Walker, Jennifer, Dudley, Joel, Cho, Judy, Schadt, Eric E, Kasarskis, Andrew, Curran, Mark, Dobrin, Radu, Hao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931595/
https://www.ncbi.nlm.nih.gov/pubmed/27336838
http://dx.doi.org/10.1038/ctg.2016.34

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