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Severe psychosocial deprivation in early childhood is associated with increased DNA methylation across a region spanning the transcription start site of CYP2E1
Exposure to adverse rearing environments including institutional deprivation and severe childhood abuse is associated with an increased risk for mental and physical health problems across the lifespan. Although the mechanisms mediating these effects are not known, recent work in rodent models sugges...
Autores principales: | Kumsta, R, Marzi, S J, Viana, J, Dempster, E L, Crawford, B, Rutter, M, Mill, J, Sonuga-Barke, E J S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931613/ https://www.ncbi.nlm.nih.gov/pubmed/27271856 http://dx.doi.org/10.1038/tp.2016.95 |
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