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Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure
OBJECTIVES: To evaluate the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD) optical coherence tomography (OCT) in non-diabetic patients with end-stage-renal-failure (ESRF) undergoing hemodialysis (HD). METHODS: This is a prospective and observational study. Both eye...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Saudi Medical Journal
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931645/ https://www.ncbi.nlm.nih.gov/pubmed/27279510 http://dx.doi.org/10.15537/smj.2016.6.13928 |
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author | Atilgan, Cemile U. Guven, Dilek Akarsu, Ozge P. Sakaci, Tamer Sendul, Selam Y. Baydar, Yasemin Atilgan, Kadir G. Turker, Ibrahim C. |
author_facet | Atilgan, Cemile U. Guven, Dilek Akarsu, Ozge P. Sakaci, Tamer Sendul, Selam Y. Baydar, Yasemin Atilgan, Kadir G. Turker, Ibrahim C. |
author_sort | Atilgan, Cemile U. |
collection | PubMed |
description | OBJECTIVES: To evaluate the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD) optical coherence tomography (OCT) in non-diabetic patients with end-stage-renal-failure (ESRF) undergoing hemodialysis (HD). METHODS: This is a prospective and observational study. Both eyes of 20 patients receiving HD (group 1) and 34 control patients (group 2) were evaluated by FD-OCT. Macular and RNFL thicknesses were compared between groups and their correlation with age, duration of HD, and gender were examined. In group 1, macular and RNFL thicknesses were evaluated before and shortly after HD in the first day, first and sixth months. RESULTS: In group 1, pre-HD temporal, inferior, average RNFL thicknesses were thinner than group 2. This thinning did not correlate with duration of HD, age and gender. Pre-HD macular thicknesses were thinner than group 2. These thinnings did not correlate with age, but the thinnings at superior, nasal and average thickness correlated negatively with duration of HD. Nasal, temporal, and average macular thicknesses were thinner in female patients. The thickenings of RNFL and macula that were observed in the after HD first day and first month did not showed consistency in the sixth month except superior quadrant RNFL. CONCLUSION: Macular and RNFL thicknesses of patients receiving HD were less than the normal population. Age has no effect on these thinnings. The duration of HD affects more than gender. Hemodialysis session causes a consistent increase in superior quadrant RNFL. |
format | Online Article Text |
id | pubmed-4931645 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Saudi Medical Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-49316452016-07-07 Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure Atilgan, Cemile U. Guven, Dilek Akarsu, Ozge P. Sakaci, Tamer Sendul, Selam Y. Baydar, Yasemin Atilgan, Kadir G. Turker, Ibrahim C. Saudi Med J Original Article OBJECTIVES: To evaluate the thicknesses of retinal nerve fiber layer (RNFL) and macula by fourier-domain (FD) optical coherence tomography (OCT) in non-diabetic patients with end-stage-renal-failure (ESRF) undergoing hemodialysis (HD). METHODS: This is a prospective and observational study. Both eyes of 20 patients receiving HD (group 1) and 34 control patients (group 2) were evaluated by FD-OCT. Macular and RNFL thicknesses were compared between groups and their correlation with age, duration of HD, and gender were examined. In group 1, macular and RNFL thicknesses were evaluated before and shortly after HD in the first day, first and sixth months. RESULTS: In group 1, pre-HD temporal, inferior, average RNFL thicknesses were thinner than group 2. This thinning did not correlate with duration of HD, age and gender. Pre-HD macular thicknesses were thinner than group 2. These thinnings did not correlate with age, but the thinnings at superior, nasal and average thickness correlated negatively with duration of HD. Nasal, temporal, and average macular thicknesses were thinner in female patients. The thickenings of RNFL and macula that were observed in the after HD first day and first month did not showed consistency in the sixth month except superior quadrant RNFL. CONCLUSION: Macular and RNFL thicknesses of patients receiving HD were less than the normal population. Age has no effect on these thinnings. The duration of HD affects more than gender. Hemodialysis session causes a consistent increase in superior quadrant RNFL. Saudi Medical Journal 2016-06 /pmc/articles/PMC4931645/ /pubmed/27279510 http://dx.doi.org/10.15537/smj.2016.6.13928 Text en Copyright: © Saudi Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Atilgan, Cemile U. Guven, Dilek Akarsu, Ozge P. Sakaci, Tamer Sendul, Selam Y. Baydar, Yasemin Atilgan, Kadir G. Turker, Ibrahim C. Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
title | Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
title_full | Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
title_fullStr | Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
title_full_unstemmed | Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
title_short | Effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
title_sort | effects of hemodialysis on macular and retinal nerve fiber layer thicknesses in non-diabetic patients with end stage renal failure |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931645/ https://www.ncbi.nlm.nih.gov/pubmed/27279510 http://dx.doi.org/10.15537/smj.2016.6.13928 |
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