Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions

Constitutive functional HIF-2α was recently identified in cancer and stem cell lines under normoxia. In this study, BEAS-2B, a bronchial epithelial cell line, was shown to constitutively express active HIF-2α under normoxia and exhibit markers of pluripotency including Oct-4, Nanog, and sphere forma...

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Detalles Bibliográficos
Autores principales: Lee, Meng-Chang, Huang, Hsin-Ju, Chang, Tzu-Hao, Huang, Hsieh-Chou, Hsieh, Shen-Yuan, Chen, Yi-Siou, Chou, Wei-Yuan, Chiang, Chiao-Hsi, Lai, Ching-Huang, Shiau, Chia-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931692/
https://www.ncbi.nlm.nih.gov/pubmed/27373565
http://dx.doi.org/10.1038/srep29311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931692/
https://www.ncbi.nlm.nih.gov/pubmed/27373565
http://dx.doi.org/10.1038/srep29311

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