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Fast exchange fluxes around the pyruvate node: a leaky cell model to explain the gain and loss of unlabelled and labelled metabolites in a tracer experiment

BACKGROUND: Glucose and glutamine are the two dominant metabolic substrates in cancer cells. In (13)C tracer experiments, however, it is necessary to account for all significant input substrates, as some natural (unlabelled) substrate in the medium, often derived from serum, can be metabolised by ce...

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Detalles Bibliográficos
Autores principales: Quek, Lake-Ee, Liu, Menghan, Joshi, Sanket, Turner, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931697/
https://www.ncbi.nlm.nih.gov/pubmed/27379180
http://dx.doi.org/10.1186/s40170-016-0153-9

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