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Current status of biomarker research in neurology

Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in...

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Autores principales: Polivka, Jiri, Krakorova, Kristyna, Peterka, Marek, Topolcan, Ondrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931703/
https://www.ncbi.nlm.nih.gov/pubmed/27379174
http://dx.doi.org/10.1186/s13167-016-0063-5
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author Polivka, Jiri
Polivka, Jiri
Krakorova, Kristyna
Peterka, Marek
Topolcan, Ondrej
author_facet Polivka, Jiri
Polivka, Jiri
Krakorova, Kristyna
Peterka, Marek
Topolcan, Ondrej
author_sort Polivka, Jiri
collection PubMed
description Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in neurology are described in relation to the personalized medicine and diagnostic, prognostic as well as predictive blood and cerebrospinal fluid biomarkers. Such neurological domains discussed in this work are neuro-oncology and primary brain tumors glioblastoma and oligodendroglioma, cerebrovascular diseases focusing on stroke, neurodegenerative disorders especially Alzheimer’s and Parkinson’s diseases and demyelinating diseases such as multiple sclerosis. Actual state of the art and future perspectives in diagnostics and personalized treatment in diverse domains of neurology are given.
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spelling pubmed-49317032016-07-05 Current status of biomarker research in neurology Polivka, Jiri Polivka, Jiri Krakorova, Kristyna Peterka, Marek Topolcan, Ondrej EPMA J Review Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in neurology are described in relation to the personalized medicine and diagnostic, prognostic as well as predictive blood and cerebrospinal fluid biomarkers. Such neurological domains discussed in this work are neuro-oncology and primary brain tumors glioblastoma and oligodendroglioma, cerebrovascular diseases focusing on stroke, neurodegenerative disorders especially Alzheimer’s and Parkinson’s diseases and demyelinating diseases such as multiple sclerosis. Actual state of the art and future perspectives in diagnostics and personalized treatment in diverse domains of neurology are given. BioMed Central 2016-07-04 /pmc/articles/PMC4931703/ /pubmed/27379174 http://dx.doi.org/10.1186/s13167-016-0063-5 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Polivka, Jiri
Polivka, Jiri
Krakorova, Kristyna
Peterka, Marek
Topolcan, Ondrej
Current status of biomarker research in neurology
title Current status of biomarker research in neurology
title_full Current status of biomarker research in neurology
title_fullStr Current status of biomarker research in neurology
title_full_unstemmed Current status of biomarker research in neurology
title_short Current status of biomarker research in neurology
title_sort current status of biomarker research in neurology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931703/
https://www.ncbi.nlm.nih.gov/pubmed/27379174
http://dx.doi.org/10.1186/s13167-016-0063-5
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