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Current status of biomarker research in neurology
Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931703/ https://www.ncbi.nlm.nih.gov/pubmed/27379174 http://dx.doi.org/10.1186/s13167-016-0063-5 |
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author | Polivka, Jiri Polivka, Jiri Krakorova, Kristyna Peterka, Marek Topolcan, Ondrej |
author_facet | Polivka, Jiri Polivka, Jiri Krakorova, Kristyna Peterka, Marek Topolcan, Ondrej |
author_sort | Polivka, Jiri |
collection | PubMed |
description | Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in neurology are described in relation to the personalized medicine and diagnostic, prognostic as well as predictive blood and cerebrospinal fluid biomarkers. Such neurological domains discussed in this work are neuro-oncology and primary brain tumors glioblastoma and oligodendroglioma, cerebrovascular diseases focusing on stroke, neurodegenerative disorders especially Alzheimer’s and Parkinson’s diseases and demyelinating diseases such as multiple sclerosis. Actual state of the art and future perspectives in diagnostics and personalized treatment in diverse domains of neurology are given. |
format | Online Article Text |
id | pubmed-4931703 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-49317032016-07-05 Current status of biomarker research in neurology Polivka, Jiri Polivka, Jiri Krakorova, Kristyna Peterka, Marek Topolcan, Ondrej EPMA J Review Neurology is one of the typical disciplines where personalized medicine has been recently becoming an important part of clinical practice. In this article, the brief overview and a number of examples of the use of biomarkers and personalized medicine in neurology are described. The various issues in neurology are described in relation to the personalized medicine and diagnostic, prognostic as well as predictive blood and cerebrospinal fluid biomarkers. Such neurological domains discussed in this work are neuro-oncology and primary brain tumors glioblastoma and oligodendroglioma, cerebrovascular diseases focusing on stroke, neurodegenerative disorders especially Alzheimer’s and Parkinson’s diseases and demyelinating diseases such as multiple sclerosis. Actual state of the art and future perspectives in diagnostics and personalized treatment in diverse domains of neurology are given. BioMed Central 2016-07-04 /pmc/articles/PMC4931703/ /pubmed/27379174 http://dx.doi.org/10.1186/s13167-016-0063-5 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Polivka, Jiri Polivka, Jiri Krakorova, Kristyna Peterka, Marek Topolcan, Ondrej Current status of biomarker research in neurology |
title | Current status of biomarker research in neurology |
title_full | Current status of biomarker research in neurology |
title_fullStr | Current status of biomarker research in neurology |
title_full_unstemmed | Current status of biomarker research in neurology |
title_short | Current status of biomarker research in neurology |
title_sort | current status of biomarker research in neurology |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931703/ https://www.ncbi.nlm.nih.gov/pubmed/27379174 http://dx.doi.org/10.1186/s13167-016-0063-5 |
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