Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

Aging increases the risk of type 2 diabetes, and this can be prevented by dietary restriction (DR). We have previously shown that DR inhibits the downregulation of miRNAs and their processing enzymes - mainly Dicer - that occurs with aging in mouse white adipose tissue (WAT). Here we used fat-specif...

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Detalles Bibliográficos
Autores principales: Reis, Felipe C. G., Branquinho, Jéssica L. O., Brandão, Bruna B., Guerra, Beatriz A., Silva, Ismael D., Frontini, Andrea, Thomou, Thomas, Sartini, Loris, Cinti, Saverio, Kahn, C. Ronald, Festuccia, William T., Kowaltowski, Alicia J., Mori, Marcelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931827/
https://www.ncbi.nlm.nih.gov/pubmed/27241713
http://dx.doi.org/10.18632/aging.100970

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