Retinoic acid treated human dendritic cells induce T regulatory cells via the expression of CD141 and GARP which is impaired with age

Aged subjects display increased susceptibility to mucosal diseases. Retinoic Acid (RA) plays a major role in inducing tolerance in the mucosa. RA acts on Dendritic cells (DCs) to induce mucosal tolerance. Here we compared the response of DCs from aged and young individuals to RA with a view to under...

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Detalles Bibliográficos
Autores principales: Agrawal, Sudhanshu, Ganguly, Sreerupa, Tran, Alexander, Sundaram, Padmaja, Agrawal, Anshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931828/
https://www.ncbi.nlm.nih.gov/pubmed/27244900
http://dx.doi.org/10.18632/aging.100973

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