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Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
The senescence-associated secretory phenotype (SASP) has attracted attention as a mechanism that connects cellular senescence to tissue dysfunction, and specific SASP factors have been identified as systemic pro-aging factors. However, little is known about the age-dependent changes in the secretory...
Autores principales: | Hisamatsu, Daisuke, Ohno-Oishi, Michiko, Nakamura, Shiho, Mabuchi, Yo, Naka-Kaneda, Hayato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931831/ https://www.ncbi.nlm.nih.gov/pubmed/27311402 http://dx.doi.org/10.18632/aging.100982 |
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