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Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues

The senescence-associated secretory phenotype (SASP) has attracted attention as a mechanism that connects cellular senescence to tissue dysfunction, and specific SASP factors have been identified as systemic pro-aging factors. However, little is known about the age-dependent changes in the secretory...

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Detalles Bibliográficos
Autores principales: Hisamatsu, Daisuke, Ohno-Oishi, Michiko, Nakamura, Shiho, Mabuchi, Yo, Naka-Kaneda, Hayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931831/
https://www.ncbi.nlm.nih.gov/pubmed/27311402
http://dx.doi.org/10.18632/aging.100982

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