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The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks
Connectivity in a gene-gene network declines with age, typically within gene clusters. We explored the effect of short-term (3 months) graded calorie restriction (CR) (up to 40 %) on network structure of aging-associated genes in the murine hypothalamus by using conditional mutual information. The n...
Autores principales: | Derous, Davina, Mitchell, Sharon E., Green, Cara L., Wang, Yingchun, Han, Jing Dong J., Chen, Luonan, Promislow, Daniel E.L., Lusseau, David, Speakman, John R., Douglas, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931844/ https://www.ncbi.nlm.nih.gov/pubmed/27115072 http://dx.doi.org/10.18632/aging.100944 |
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