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Decreased Pregnane X Receptor Expression in Children with Active Crohn’s Disease

Expression of the pregnane X receptor (PXR) has been reported to be decreased in animal models of inflammatory bowel disease (IBD). To investigate the differential expression of PXR in children with Crohn’s disease, a type of IBD, RNA was extracted from archived intestinal biopsies from 18 children...

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Detalles Bibliográficos
Autores principales:	Shakhnovich, Valentina, Vyhlidal, Carrie, Friesen, Craig, Hildreth, Amber, Singh, Vivekanand, Daniel, James, Kearns, Gregory L., Leeder, J. Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:	Special Section on Pediatric Drug Disposition and Pharmacokinetics—Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931888/ https://www.ncbi.nlm.nih.gov/pubmed/27013401 http://dx.doi.org/10.1124/dmd.115.068742

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