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KYNA analogue SZR72 modifies CFA-induced dural inflammation- regarding expression of pERK1/2 and IL-1β in the rat trigeminal ganglion

BACKGROUND: Neurogenic inflammation has for decades been considered an important part of migraine pathophysiology. In the present study, we asked the question if administration of a novel kynurenic acid analogue (SZR72), precursor of an excitotoxin antagonist and anti-inflammatory substance, can mod...

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Detalles Bibliográficos
Autores principales:	Lukács, M., Warfvinge, K., Kruse, L. S., Tajti, J., Fülöp, F., Toldi, J., Vécsei, L., Edvinsson, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Milan 2016
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932003/ https://www.ncbi.nlm.nih.gov/pubmed/27377707 http://dx.doi.org/10.1186/s10194-016-0654-5

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