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Imaging in-vivo tau pathology in Alzheimer’s disease with THK5317 PET in a multimodal paradigm

PURPOSE: The aim of this study was to explore the cerebral distribution of the tau-specific PET tracer [(18)F]THK5317 (also known as (S)-[(18)F]THK5117) retention in different stages of Alzheimer’s disease; and study any associations with markers of hypometabolism and amyloid-beta deposition. METHOD...

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Detalles Bibliográficos
Autores principales: Chiotis, Konstantinos, Saint-Aubert, Laure, Savitcheva, Irina, Jelic, Vesna, Andersen, Pia, Jonasson, My, Eriksson, Jonas, Lubberink, Mark, Almkvist, Ove, Wall, Anders, Antoni, Gunnar, Nordberg, Agneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932128/
https://www.ncbi.nlm.nih.gov/pubmed/26996778
http://dx.doi.org/10.1007/s00259-016-3363-z