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Regulation of CYP27B1 mRNA Expression in Primary Human Osteoblasts

The enzyme 1α-hydroxylase (gene CYP27B1) catalyzes the synthesis of 1,25(OH)(2)D in both renal and bone cells. While renal 1α-hydroxylase is tightly regulated by hormones and 1,25(OH)(2)D itself, the regulation of 1α-hydroxylase in bone cells is poorly understood. The aim of this study was to invest...

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Detalles Bibliográficos
Autores principales: van der Meijden, K., van Essen, H. W., Bloemers, F. W., Schulten, E. A. J. M., Lips, P., Bravenboer, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932130/
https://www.ncbi.nlm.nih.gov/pubmed/27016371
http://dx.doi.org/10.1007/s00223-016-0131-9