Cargando…

In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [(18)F]GE-180 and effect of docosahexaenoic acid

PURPOSE: Traumatic spinal cord injury (SCI) is a devastating condition which affects millions of people worldwide causing major disability and substantial socioeconomic burden. There are currently no effective treatments. Modulating the neuroinflammatory (NI) response after SCI has evolved as a majo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tremoleda, J. L., Thau-Zuchman, O., Davies, M., Foster, J., Khan, I., Vadivelu, K. C., Yip, P. K., Sosabowski, J., Trigg, W., Michael-Titus, A. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932147/ https://www.ncbi.nlm.nih.gov/pubmed/27154521 http://dx.doi.org/10.1007/s00259-016-3391-8

Ejemplares similares

TSPO PET signal using [(18)F]GE180 is associated with survival in recurrent gliomas
por: Quach, Stefanie, et al.
Publicado: (2022)

(18)F-Radiolabeled Translocator Protein (TSPO) PET Tracers: Recent Development of TSPO Radioligands and Their Application to PET Study
por: Luu, Truong Giang, et al.
Publicado: (2022)

Positron Emission Tomography Imaging of Macrophages in Atherosclerosis with (18)F-GE-180, a Radiotracer for Translocator Protein (TSPO)
por: Hellberg, Sanna, et al.
Publicado: (2018)

In response to: Anatomy of (18)F-GE180, a failed radioligand for the TSPO protein
por: Albert, Nathalie L., et al.
Publicado: (2020)

TSPO imaging using the novel PET ligand [(18)F]GE-180: quantification approaches in patients with multiple sclerosis
por: Vomacka, Lena, et al.
Publicado: (2017)

Longitudinal [(18)F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model
por: Holzgreve, Adrien, et al.
Publicado: (2022)

Data on specificity of [(18)F]GE180 uptake for TSPO expression in rodent brain and myocardium
por: Deussing, Maximilian, et al.
Publicado: (2018)

Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand (18)F-GE-180 and comparison with (18)F-FDG and DCE-MRI
por: de Groot, Marius, et al.
Publicado: (2019)

Impact of TSPO Receptor Polymorphism on [(18)F]GE-180 Binding in Healthy Brain and Pseudo-Reference Regions of Neurooncological and Neurodegenerative Disorders
por: Vettermann, Franziska J., et al.
Publicado: (2021)

PET Imaging of Neuro-Inflammation with Tracers Targeting the Translocator Protein (TSPO), a Systematic Review: From Bench to Bedside
por: Corica, Ferdinando, et al.
Publicado: (2023)

Cellular Sources and Regional Variations in the Expression of the Neuroinflammatory Marker Translocator Protein (TSPO) in the Normal Brain
por: Betlazar, Calina, et al.
Publicado: (2018)

The mitochondrial protein TSPO in Alzheimer’s disease: relation to the severity of AD pathology and the neuroinflammatory environment
por: Garland, Emma F., et al.
Publicado: (2023)

Brain Phospholipid Precursors Administered Post-Injury Reduce Tissue Damage and Improve Neurological Outcome in Experimental Traumatic Brain Injury
por: Thau-Zuchman, Orli, et al.
Publicado: (2019)

The role of TSPO PET in assessing neuroinflammation
por: Crawshaw, Ania A., et al.
Publicado: (2017)

Supervised clustering for TSPO PET imaging
por: Schubert, Julia, et al.
Publicado: (2021)

Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats
por: Sridharan, Sujata, et al.
Publicado: (2016)

PET Imaging of Microglial Activation—Beyond Targeting TSPO
por: Janssen, Bieneke, et al.
Publicado: (2018)

Imaging adipose tissue browning using the TSPO-18kDa tracer [(18)F]FEPPA
por: Hartimath, S.V., et al.
Publicado: (2019)

[(18)F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease
por: James, Michelle L., et al.
Publicado: (2017)

Imaging neuroinflammation in multiple sclerosis using TSPO-PET
por: Airas, Laura, et al.
Publicado: (2015)

Recent developments on PET radiotracers for TSPO and their applications in neuroimaging
por: Zhang, Lingling, et al.
Publicado: (2021)

Identifying improved TSPO PET imaging probes through biomathematics: The impact of multiple TSPO binding sites in vivo
por: Guo, Qi, et al.
Publicado: (2012)

Radiosynthesis of (R,S)‐[(18)F]GE387: A Potential PET Radiotracer for Imaging Translocator Protein 18 kDa (TSPO) with Low Binding Sensitivity to the Human Gene Polymorphism rs6971
por: Qiao, Luxi, et al.
Publicado: (2019)

Kinetic analysis of the translocator protein positron emission tomography ligand [(18)F]GE-180 in the human brain
por: Feeney, Claire, et al.
Publicado: (2016)

Perspective: Solving the Heterogeneity Conundrum of TSPO PET Imaging in Psychosis
por: De Picker, Livia, et al.
Publicado: (2020)

Longitudinal change in TSPO PET imaging in progressive multiple sclerosis
por: Kang, Yeona, et al.
Publicado: (2021)

Assessment of the In Vivo Relationship Between Cerebral Hypometabolism, Tau Deposition, TSPO Expression, and Synaptic Density in a Tauopathy Mouse Model: a Multi-tracer PET Study
por: Endepols, Heike, et al.
Publicado: (2022)

High phenylalanine concentrations induce demyelination and microglial activation in mouse cerebellar organotypic slices
por: Thau-Zuchman, Orli, et al.
Publicado: (2022)

(11)C-DPA-713 Versus (18)F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke
por: Chaney, Aisling, et al.
Publicado: (2019)

[(11)C]-DPA-713 and [(18)F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [(11)C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis
por: Doorduin, Janine, et al.
Publicado: (2009)

Imidazoline-I2 PET Tracers in Neuroimaging
por: Parker, Christine A., et al.
Publicado: (2023)

Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders
por: Werry, Eryn L., et al.
Publicado: (2019)

Kinetic modeling and parameter estimation of TSPO PET imaging in the human brain
por: Wimberley, Catriona, et al.
Publicado: (2021)

PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects
por: Richards, Erica M., et al.
Publicado: (2018)

Alteration of neuroinflammation detected by (18)F-GE180 PET imaging in place-conditioned rats with morphine withdrawal
por: Li, Junpeng, et al.
Publicado: (2021)

Protocols for Dual Tracer PET/SPECT Preclinical Imaging
por: Blower, Julia E., et al.
Publicado: (2020)

Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study
por: Buck, Jason R., et al.
Publicado: (2015)

A measurement of the photonuclear interactions of 180 GeV muons in iron
por: Alexa, C, et al.
Publicado: (2003)

PET Tracers for Clinical Imaging of Breast Cancer
por: Peñuelas, Iván, et al.
Publicado: (2012)

Beyond FDG: novel PET tracers for cancer imaging
por: Hicks, Rodney J
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_gd7uk85pgua4k4i8e4e2jceok3