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A novel flow cytometric-based method to measure kinase inhibition in sputum from COPD subjects

INTRODUCTION: Janus kinases (JAKs) regulate inflammatory gene expression through phosphorylation of signal transducer and activator of transcription (STAT) proteins. Expression of STAT proteins is increased in chronic obstructive pulmonary disease (COPD), and may be involved in driving chronic infla...

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Detalles Bibliográficos
Autores principales:	Nicholson, G C, Holloway, R A, Leaker, B R, Kilty, I, Salganik, M, Tan, L, Barnes, P J, Donnelly, L E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Respiratory Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932304/ https://www.ncbi.nlm.nih.gov/pubmed/27403320 http://dx.doi.org/10.1136/bmjresp-2016-000140

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