A Presenilin-2–ARF4 trafficking axis modulates Notch signaling during epidermal differentiation

How primary cilia impact epidermal growth and differentiation during embryogenesis is poorly understood. Here, we show that during skin development, Notch signaling occurs within the ciliated, differentiating cells of the first few suprabasal epidermal layers. Moreover, both Notch signaling and cili...

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Detalles Bibliográficos
Autores principales: Ezratty, Ellen J., Pasolli, H. Amalia, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932368/
https://www.ncbi.nlm.nih.gov/pubmed/27354375
http://dx.doi.org/10.1083/jcb.201508082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932368/
https://www.ncbi.nlm.nih.gov/pubmed/27354375
http://dx.doi.org/10.1083/jcb.201508082

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