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A Presenilin-2–ARF4 trafficking axis modulates Notch signaling during epidermal differentiation
How primary cilia impact epidermal growth and differentiation during embryogenesis is poorly understood. Here, we show that during skin development, Notch signaling occurs within the ciliated, differentiating cells of the first few suprabasal epidermal layers. Moreover, both Notch signaling and cili...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932368/ https://www.ncbi.nlm.nih.gov/pubmed/27354375 http://dx.doi.org/10.1083/jcb.201508082 |