Exosomes expand the sphere of influence of Eph receptors and ephrins

Membrane-anchored Eph receptors and ephrins represent a ubiquitous intercellular communication system that typically engages at sites of cell–cell contact to initiate bidirectional signaling. Gong et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601085) show that cells can deploy the Eph...

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Detalles Bibliográficos
Autor principal: Pasquale, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932377/
https://www.ncbi.nlm.nih.gov/pubmed/27354377
http://dx.doi.org/10.1083/jcb.201606074
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author Pasquale, Elena B.
author_facet Pasquale, Elena B.
author_sort Pasquale, Elena B.
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description Membrane-anchored Eph receptors and ephrins represent a ubiquitous intercellular communication system that typically engages at sites of cell–cell contact to initiate bidirectional signaling. Gong et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601085) show that cells can deploy the EphB2 receptor on exosomes to activate ephrinB signaling and collapse the growth cones of distant neurons.
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spelling pubmed-49323772017-01-04 Exosomes expand the sphere of influence of Eph receptors and ephrins Pasquale, Elena B. J Cell Biol Commentary Membrane-anchored Eph receptors and ephrins represent a ubiquitous intercellular communication system that typically engages at sites of cell–cell contact to initiate bidirectional signaling. Gong et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601085) show that cells can deploy the EphB2 receptor on exosomes to activate ephrinB signaling and collapse the growth cones of distant neurons. The Rockefeller University Press 2016-07-04 /pmc/articles/PMC4932377/ /pubmed/27354377 http://dx.doi.org/10.1083/jcb.201606074 Text en © 2016 Pasquale This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Pasquale, Elena B.
Exosomes expand the sphere of influence of Eph receptors and ephrins
title Exosomes expand the sphere of influence of Eph receptors and ephrins
title_full Exosomes expand the sphere of influence of Eph receptors and ephrins
title_fullStr Exosomes expand the sphere of influence of Eph receptors and ephrins
title_full_unstemmed Exosomes expand the sphere of influence of Eph receptors and ephrins
title_short Exosomes expand the sphere of influence of Eph receptors and ephrins
title_sort exosomes expand the sphere of influence of eph receptors and ephrins
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932377/
https://www.ncbi.nlm.nih.gov/pubmed/27354377
http://dx.doi.org/10.1083/jcb.201606074
work_keys_str_mv AT pasqualeelenab exosomesexpandthesphereofinfluenceofephreceptorsandephrins

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