Cargando…

Understanding the dynamics of monomeric, dimeric, and tetrameric α‐synuclein structures in water

Human α‐synuclein (αS) is an intrinsically disordered protein associated with Parkinson's disease. Molecular mechanisms of corruptive misfolding and aggregation of αS resulting in the disease, as well as the structure and other properties of the corresponding oligomers are not entirely understo...

Descripción completa

Detalles Bibliográficos
Autores principales: Mane, Jonathan Y., Stepanova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932447/
https://www.ncbi.nlm.nih.gov/pubmed/27398307
http://dx.doi.org/10.1002/2211-5463.12069