The modification of the thrombin generation test for the clinical assessment of dabigatran etexilate efficiency

A new oral anticoagulant, dabigatran etexilate (DE, a prodrug of direct thrombin inhibitor (DTI) dabigatran), has been used clinically to prevent thrombosis. The assessment of dabigatran efficiency is necessary in some clinical cases, such as renal insufficiency, risk of bleeding, and drug interacti...

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Detalles Bibliográficos
Autores principales: Gribkova, Irina V., Lipets, Elena N., Rekhtina, Irina G., Bernakevich, Alex I., Ayusheev, Dorzho B., Ovsepyan, Ruzanna A., Ataullakhanov, Fazoil I., Sinauridze, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932519/
https://www.ncbi.nlm.nih.gov/pubmed/27377013
http://dx.doi.org/10.1038/srep29242

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