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RIP3 induces ischemic neuronal DNA degradation and programmed necrosis in rat via AIF

We have reported that nuclear translocation of Receptor-interacting protein 3 (RIP3) involves in neuronal programmed necrosis after 20-min global cerebral ischemia/reperfusion (I/R) injury. Herein, the underlying mechanisms and the nuclear role of RIP3 were investigated further. The necroptosis inhi...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Wang, Jingye, Song, Xinghui, Qu, Lindi, Wei, Ruili, He, Fangping, Wang, Kai, Luo, Benyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932529/
https://www.ncbi.nlm.nih.gov/pubmed/27377128
http://dx.doi.org/10.1038/srep29362