Accounting for treatment by center interaction in sample size determinations and the use of surrogate outcomes in the pessary for the prevention of preterm birth trial: a simulation study

BACKGROUND: The Pessary for the Prevention of Preterm Birth Study (PS3) is an international, multicenter, randomized clinical trial designed to examine the effectiveness of the Arabin pessary in preventing preterm birth in pregnant women with a short cervix. During the design of the study two method...

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Detalles Bibliográficos
Autor principal: Willan, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932689/
https://www.ncbi.nlm.nih.gov/pubmed/27378231
http://dx.doi.org/10.1186/s13063-016-1433-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932689/
https://www.ncbi.nlm.nih.gov/pubmed/27378231
http://dx.doi.org/10.1186/s13063-016-1433-y

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