Cargando…
CD80 down-regulation is associated to aberrant DNA methylation in non-inflammatory colon carcinogenesis
BACKGROUND: The lack of positive costimulatory molecules represents one of the mechanisms by which tumor cells evade immune surveillance. Promoter hypermethylation plays a major role in cancer development through transcriptional silencing of critical genes. The aim of this study was to examine the e...
Autores principales: | Scarpa, Marco, Scarpa, Melania, Castagliuolo, Ignazio, Erroi, Francesca, Basato, Silvia, Brun, Paola, Angriman, Imerio, Castoro, Carlo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932699/ https://www.ncbi.nlm.nih.gov/pubmed/27377375 http://dx.doi.org/10.1186/s12885-016-2405-z |
Ejemplares similares
-
Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC
por: Scarpa, Marco, et al.
Publicado: (2016) -
CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis
por: Scarpa, Marco, et al.
Publicado: (2015) -
Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions and its expression is increased by oxidative stress through STAT3 in colon cancer cells
por: Marchiori, Chiara, et al.
Publicado: (2019) -
MLH1 Deficiency Down-Regulates TLR4 Expression in Sporadic Colorectal Cancer
por: Scarpa, Melania, et al.
Publicado: (2021) -
Fistula-Related Cancer in Crohn’s Disease: A Systematic Review
por: Kotsafti, Andromachi, et al.
Publicado: (2021)