Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review

BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food a...

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Detalles Bibliográficos
Autores principales: Dhami, Sangeeta, Nurmatov, Ulugbek, Pajno, Giovanni Battista, Fernandez-Rivas, Montserrat, Muraro, Antonella, Roberts, Graham, Akdis, Cezmi, Alvaro-Lozano, Montserrat, Beyer, Kirsten, Bindslev-Jensen, Carsten, Burks, Wesley, du Toit, George, Ebisawa, Motohiro, Eigenmann, Philippe, Knol, Edward, Makela, Mika, Nadeau, Kari Christine, O’Mahony, Liam, Papadopoulos, Nikolaos, Poulsen, Lars, Sackesen, Cansin, Sampson, Hugh, Santos, Alexandra, van Ree, Ronald, Timmermans, Frans, Sheikh, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932703/
https://www.ncbi.nlm.nih.gov/pubmed/27382460
http://dx.doi.org/10.1186/s13601-016-0113-z
Descripción
Sumario:BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. METHODS: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. DISCUSSION: The findings from this review will be used to inform the development of recommendations for EAACI’s Guidelines on AIT. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13601-016-0113-z) contains supplementary material, which is available to authorized users.

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