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Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines
BACKGROUND: The refractory nature of many cancers remains the main health challenge over the past century. The epigenetic drug, decitabine (DAC), represents one of the most promising therapeutic agents in cancers particularly in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Howev...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932764/ https://www.ncbi.nlm.nih.gov/pubmed/27382363 http://dx.doi.org/10.1186/s12014-016-9115-z |