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Prevalence of genital human papillomavirus among rural and urban populations in southern Yunnan province, China
This study was designed to investigate and compare the HPV prevalence, genotypes distribution and associated risk factors in rural and urban women living in Xishuang Banna district, in the province of Yunnan. A total of 177 and 190 women from rural and urban areas were engaged, respectively. HPV DNA...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932820/ https://www.ncbi.nlm.nih.gov/pubmed/27254662 http://dx.doi.org/10.1590/1414-431X20165254 |
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author | Baloch, Z. Yuan, T. Yindi, S. Feng, Y. Tai, W. Liu, Y. Liu, L. Zhang, A. Wang, B. Wu, X. Xia, X. |
author_facet | Baloch, Z. Yuan, T. Yindi, S. Feng, Y. Tai, W. Liu, Y. Liu, L. Zhang, A. Wang, B. Wu, X. Xia, X. |
author_sort | Baloch, Z. |
collection | PubMed |
description | This study was designed to investigate and compare the HPV prevalence, genotypes distribution and associated risk factors in rural and urban women living in Xishuang Banna district, in the province of Yunnan. A total of 177 and 190 women from rural and urban areas were engaged, respectively. HPV DNA was amplified using the L1 consensus primers system (MY09/11 and GP5/6) and HPV GenoArray test was conducted for genotyping. Proportions were compared by chi-square test, and logistic regression was used to evaluate risk factors. A total of 54 women were positive for HPV DNA. Among rural women, 23 women were positive for HPV infection, of which 21 showed a single infection and 2 had a multiple infection. HPV-16 (10/23) was the most prevalent genotype followed by HPV-52 (5/23), and HPV-58 (5/23). Urban women had a higher infection rate for overall HPV (31/54) and for multiple genotype infection (8/31). HPV-52 (9/31) was the most prevalent genotype followed by HPV-39 (7/31) and HPV-68 (5/31). The age-specific HPV prevalence was also different between rural and urban women. In urban area, women with age <35 years had the highest HPV prevalence, which declined thereafter as age advanced. However, in rural women the highest HPV prevalence was observed in an older age group (>56 years). Ethnicity, smoking and parity were significantly associated with HPV infection among urban women. Our study demonstrates that HPV prevalence and genotype distribution varies among women from rural and urban areas in the south of Yunnan. |
format | Online Article Text |
id | pubmed-4932820 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Associação Brasileira de Divulgação Científica |
record_format | MEDLINE/PubMed |
spelling | pubmed-49328202016-07-15 Prevalence of genital human papillomavirus among rural and urban populations in southern Yunnan province, China Baloch, Z. Yuan, T. Yindi, S. Feng, Y. Tai, W. Liu, Y. Liu, L. Zhang, A. Wang, B. Wu, X. Xia, X. Braz J Med Biol Res Clinical Investigation This study was designed to investigate and compare the HPV prevalence, genotypes distribution and associated risk factors in rural and urban women living in Xishuang Banna district, in the province of Yunnan. A total of 177 and 190 women from rural and urban areas were engaged, respectively. HPV DNA was amplified using the L1 consensus primers system (MY09/11 and GP5/6) and HPV GenoArray test was conducted for genotyping. Proportions were compared by chi-square test, and logistic regression was used to evaluate risk factors. A total of 54 women were positive for HPV DNA. Among rural women, 23 women were positive for HPV infection, of which 21 showed a single infection and 2 had a multiple infection. HPV-16 (10/23) was the most prevalent genotype followed by HPV-52 (5/23), and HPV-58 (5/23). Urban women had a higher infection rate for overall HPV (31/54) and for multiple genotype infection (8/31). HPV-52 (9/31) was the most prevalent genotype followed by HPV-39 (7/31) and HPV-68 (5/31). The age-specific HPV prevalence was also different between rural and urban women. In urban area, women with age <35 years had the highest HPV prevalence, which declined thereafter as age advanced. However, in rural women the highest HPV prevalence was observed in an older age group (>56 years). Ethnicity, smoking and parity were significantly associated with HPV infection among urban women. Our study demonstrates that HPV prevalence and genotype distribution varies among women from rural and urban areas in the south of Yunnan. Associação Brasileira de Divulgação Científica 2016-05-31 /pmc/articles/PMC4932820/ /pubmed/27254662 http://dx.doi.org/10.1590/1414-431X20165254 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Investigation Baloch, Z. Yuan, T. Yindi, S. Feng, Y. Tai, W. Liu, Y. Liu, L. Zhang, A. Wang, B. Wu, X. Xia, X. Prevalence of genital human papillomavirus among rural and urban populations in southern Yunnan province, China |
title | Prevalence of genital human papillomavirus among rural and urban
populations in southern Yunnan province, China |
title_full | Prevalence of genital human papillomavirus among rural and urban
populations in southern Yunnan province, China |
title_fullStr | Prevalence of genital human papillomavirus among rural and urban
populations in southern Yunnan province, China |
title_full_unstemmed | Prevalence of genital human papillomavirus among rural and urban
populations in southern Yunnan province, China |
title_short | Prevalence of genital human papillomavirus among rural and urban
populations in southern Yunnan province, China |
title_sort | prevalence of genital human papillomavirus among rural and urban
populations in southern yunnan province, china |
topic | Clinical Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932820/ https://www.ncbi.nlm.nih.gov/pubmed/27254662 http://dx.doi.org/10.1590/1414-431X20165254 |
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