Insights into the Tunnel Mechanism of Cholesteryl Ester Transfer Protein through All-atom Molecular Dynamics Simulations

Cholesteryl ester transfer protein (CETP) mediates cholesteryl ester (CE) transfer from the atheroprotective high density lipoprotein (HDL) cholesterol to the atherogenic low density lipoprotein cholesterol. In the past decade, this property has driven the development of CETP inhibitors, which have...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, Dongsheng, Rames, Matthew, Zhang, Xing, Zhang, Lei, Zhang, Shengli, Ren, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933163/
https://www.ncbi.nlm.nih.gov/pubmed/27143480
http://dx.doi.org/10.1074/jbc.M116.715565

Ejemplares similares

Ejemplares similares