The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule

Agrin, a multidomain proteoglycan and neurotrypsin, a neuronal serine protease, are important for forming (neuromuscular) synapses. Proteolytical activity of neurotrypsin produces a C-terminal fragment of agrin, termed CAF, of approximately 22 kDA molecular size which also circulates in blood. The p...

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Detalles Bibliográficos
Autores principales: Daryadel, Arezoo, Haubitz, Monika, Figueiredo, Marta, Steubl, Dominik, Roos, Marcel, Mäder, Armin, Hettwer, Stefan, Wagner, Carsten A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933355/
https://www.ncbi.nlm.nih.gov/pubmed/27380275
http://dx.doi.org/10.1371/journal.pone.0157905

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