Cargando…

Role of PKCδ in Enhanced Expression of Gqα/PLCβ1 Proteins and VSMC Hypertrophy in Spontaneously Hypertensive Rats

Gqα signaling has been implicated in cardiac hypertrophy. In addition, angiotensin II (Ang II) was also shown to induce its hypertrophic effect through Gqα and PKCδ activation. We recently showed the role of enhanced expression of Gqα/PLCβ1 proteins in vascular smooth muscle cell (VSMC) hypertrophy,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Atef, Mohammed Emehdi, Anand-Srivastava, Madhu B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933357/ https://www.ncbi.nlm.nih.gov/pubmed/27379421 http://dx.doi.org/10.1371/journal.pone.0157955

Ejemplares similares

Natriuretic peptide receptor‐C‐mediated attenuation of vascular smooth muscle cell hypertrophy involves Gqα/PLCβ1 proteins and ROS‐associated signaling
por: Jain, Ashish, et al.
Publicado: (2017)

Selective regulation of osteoclast adhesion and spreading by PLCγ/PKCα-PKCδ/RhoA-Rac1 signaling
por: Kim, Jin-Man, et al.
Publicado: (2018)

PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022)

Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling
por: Pastuhov, Strahil Iv., et al.
Publicado: (2012)

PKCδ Localization at the Membrane Increases Matrix Traction Force Dependent on PLCγ1/EGFR Signaling
por: Jamison, Joshua, et al.
Publicado: (2013)

Dissociation of the G protein βγ from the Gq–PLCβ complex partially attenuates PIP2 hydrolysis
por: Kankanamge, Dinesh, et al.
Publicado: (2021)

Suppression of Gq and PLC gene expression has a small effect on quantum bumps in vivo in Periplaneta americana
por: Ignatova, Irina I., et al.
Publicado: (2020)

Src, PKCα, and PKCδ are required for αvβ3 integrin-mediated metastatic melanoma invasion
por: Putnam, Andrew J, et al.
Publicado: (2009)

Overexpressed PKCδ Downregulates the Expression of PKCα in B16F10 Melanoma: Induction of Apoptosis by PKCδ via Ceramide Generation
por: Halder, Kuntal, et al.
Publicado: (2014)

Germacrone alleviates okadaic acid-induced neurotoxicity in PC12 cells via M1 muscarinic receptor-mediated Galphaq (Gq)/phospholipase C beta (PLCβ)/ protein kinase C (PKC) signaling
por: Lin, Mingqin, et al.
Publicado: (2022)

PKCδ Blues for the β-Cell
por: Schmitz-Peiffer, Carsten, et al.
Publicado: (2010)

Knockdown of Inhibitory Guanine Nucleotide Binding Protein Giα‐2 by Antisense Oligodeoxynucleotides Attenuates the Development of Hypertension and Tachycardia in Spontaneously Hypertensive Rats
por: Ali El‐Basyuni, Yousra, et al.
Publicado: (2016)

Excess of Gβ(e) over Gqα(e) in vivo prevents dark, spontaneous activity of Drosophila photoreceptors
por: Elia, Natalie, et al.
Publicado: (2005)

Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo
por: Zhu, Meng, et al.
Publicado: (2017)

Role of FGFR2b expression and signaling in keratinocyte differentiation: sequential involvement of PKCδ and PKCα
por: Rosato, Benedetta, et al.
Publicado: (2018)

Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008)

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension
por: Sun, Hai-Jian, et al.
Publicado: (2017)

Calretinin Participates in Regulating Steroidogenesis by PLC-Ca(2+)-PKC Pathway in Leydig Cells
por: Xu, Wendan, et al.
Publicado: (2018)

PKCα and PKCδ Regulate ADAM17-Mediated Ectodomain Shedding of Heparin Binding-EGF through Separate Pathways
por: Kveiborg, Marie, et al.
Publicado: (2011)

Rosuvastatin-attenuated heart failure in aged spontaneously hypertensive rats via PKCα/β2 signal pathway
por: Qiu, Zhaohui, et al.
Publicado: (2012)

Gq-Coupled Receptors in Autoimmunity
por: Zhang, Lu, et al.
Publicado: (2016)

The Gαh-PLCδ1 signaling axis drives metastatic progression in triple-negative breast cancer
por: Huang, Shang-Pen, et al.
Publicado: (2017)

B7-H4 expression is upregulated by PKCδ activation and contributes to PKCδ-induced cell motility in colorectal cancer
por: Zhou, Bin, et al.
Publicado: (2022)

Roles and mechanisms of TRPC3 and the PLCγ/PKC/CPI-17 signaling pathway in regulating parturition
por: Chen, Jing, et al.
Publicado: (2018)

Roles and mechanisms of TRPC3 and the PLCγ/PKC/CPI-17 signaling pathway in regulating parturition
por: Chen, Jing, et al.
Publicado: (2018)

Gq/11-Mediated Signaling and Hypertrophy in Mice with Cardiac-Specific Transgenic Expression of Regulator of G-Protein Signaling 2
por: Park-Windhol, Cindy, et al.
Publicado: (2012)

PKCδ regulates the vascular biology in diabetic atherosclerosis
por: Qin, Peiliang, et al.
Publicado: (2023)

PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice
por: Niino, Yuko S., et al.
Publicado: (2021)

Oxidative Stress Mediates the Disruption of Airway Epithelial Tight Junctions through a TRPM2-PLCγ1-PKCα Signaling Pathway
por: Xu, Rui, et al.
Publicado: (2013)

AKT Mediates Adiponectin-Dependent Regulation of VSMC Phenotype
por: Cullen, Abigail E., et al.
Publicado: (2023)

Osmotically evoked PLCδ1-dependent translocation of ΔN-TRPV1 channels in rat supraoptic neurons
por: Haan, Kirk D., et al.
Publicado: (2023)

Essential Role Of High Glucose-Induced Overexpression Of PKCβ And PKCδ In GLP-1 Resistance In Rodent Cardiomyocytes
por: Pan, Xietian, et al.
Publicado: (2019)

GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis
por: Xu, Xuehua, et al.
Publicado: (2015)

Amarogentin, a Secoiridoid Glycoside, Abrogates Platelet Activation through PLCγ2-PKC and MAPK Pathways
por: Yen, Ting-Lin, et al.
Publicado: (2014)

The Novel Functions of the PLC/PKC/PKD Signaling Axis in G Protein-Coupled Receptor-Mediated Chemotaxis of Neutrophils
por: Xu, Xuehua, et al.
Publicado: (2015)

Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing
por: Nosbisch, Jamie L., et al.
Publicado: (2020)

Protein Kinase C (Pkc)-δ Mediates Arginine-Induced Glucagon Secretion in Pancreatic α-Cells
por: Honzawa, Norikiyo, et al.
Publicado: (2022)

Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism
por: Li, Mengyao, et al.
Publicado: (2015)

Control of nuclear-cytoplasmic shuttling of Ankrd54 by PKCδ
por: Samuels, Amy L, et al.
Publicado: (2017)

The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway
por: Assad Kahn, Suzana, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k51lvm70ck8giqgdj8qsobratj