Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can facilitate detection of functional candidates and add...

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Detalles Bibliográficos
Autores principales: Du, Mengmeng, Jiao, Shuo, Bien, Stephanie A., Gala, Manish, Abecasis, Goncalo, Bezieau, Stephane, Brenner, Hermann, Butterbach, Katja, Caan, Bette J., Carlson, Christopher S., Casey, Graham, Chang-Claude, Jenny, Conti, David V., Curtis, Keith R., Duggan, David, Gallinger, Steven, Haile, Robert W., Harrison, Tabitha A., Hayes, Richard B., Hoffmeister, Michael, Hopper, John L., Hudson, Thomas J., Jenkins, Mark A., Küry, Sébastien, Le Marchand, Loic, Leal, Suzanne M., Newcomb, Polly A., Nickerson, Deborah A., Potter, John D., Schoen, Robert E., Schumacher, Fredrick R., Seminara, Daniela, Slattery, Martha L., Hsu, Li, Chan, Andrew T., White, Emily, Berndt, Sonja I., Peters, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933364/
https://www.ncbi.nlm.nih.gov/pubmed/27379672
http://dx.doi.org/10.1371/journal.pone.0157521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933364/
https://www.ncbi.nlm.nih.gov/pubmed/27379672
http://dx.doi.org/10.1371/journal.pone.0157521

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