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Selection on Network Dynamics Drives Differential Rates of Protein Domain Evolution
The long-held principle that functionally important proteins evolve slowly has recently been challenged by studies in mice and yeast showing that the severity of a protein knockout only weakly predicts that protein’s rate of evolution. However, the relevance of these studies to evolutionary changes...
Autores principales: | Mannakee, Brian K., Gutenkunst, Ryan N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933380/ https://www.ncbi.nlm.nih.gov/pubmed/27380265 http://dx.doi.org/10.1371/journal.pgen.1006132 |
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