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Selective Pro-Apoptotic Activity of Novel 3,3′-(Aryl/Alkyl-Methylene)Bis(2-Hydroxynaphthalene-1,4-Dione) Derivatives on Human Cancer Cells via the Induction Reactive Oxygen Species

Selective induction of apoptosis in cancer cells barring the normal cells is considered as an effective strategy to combat cancer. In the present study, a series of twenty-two (22) synthetic 3,3'-(aryl/alkyl-methylene)bis(2-hydroxynaphthalene-1,4-dione) bis-lawsone derivatives were assayed for...

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Detalles Bibliográficos
Autores principales: Sadhukhan, Pritam, Saha, Sukanya, Sinha, Krishnendu, Brahmachari, Goutam, Sil, Parames C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933382/
https://www.ncbi.nlm.nih.gov/pubmed/27380262
http://dx.doi.org/10.1371/journal.pone.0158694

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