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HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis

The activity of the CDK inhibitor p21 is associated with diverse biological activities, including cell proliferation, senescence, and tumorigenesis. However, the mechanisms governing transcription of p21 need to be extensively studied. In this study, we demonstrate that the high-mobility group box-c...

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Detalles Bibliográficos
Autores principales:	Chen, Yifan, Pan, Kewu, Wang, Pingzhang, Cao, Zhengyi, Wang, Weibin, Wang, Shuya, Hu, Ningguang, Xue, Junhui, Li, Hui, Jiang, Wei, Li, Gang, Zhang, Xiaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933444/ https://www.ncbi.nlm.nih.gov/pubmed/27129219 http://dx.doi.org/10.1074/jbc.M116.714147

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